xBrowse is a software toolkit for studying rare genetic diseases. It provides a variety of methods for analyzing the genetic variants that are produced by next generation sequencing (NGS) data. xBrowse contains a web interface and a (Python) analysis library, so it can be deployed as a standalone website or as part of a bioinformatics pipeline.
xBrowse is developed at the Analytic and Translational Genetics Unit (ATGU) at Massachusetts General Hospital (MGH). Our work is in collaboration with the Broad Institute of Harvard and MIT.