Stephan Ripke, MD

Stephan Ripke, MD

Research Scientist

Stephan is a key member of the Psychiatric Genomics Consortium (PGC), a collaborative effort that involves 50 datasets from research groups from 17 countries. Stephan is responsible for performing the combined analysis of the raw genetic data from the Consortium members. To do this, he has created a computer pipeline that standardizes data, imputes missing values, performs the final analysis and brings the results into displayable format (e.g. the Web based tool RICOPILI). This collection of computer programs is unique in its ability to analyze millions and millions of data points in a short period of time, a critical ability that has allowed genome-wide association studies of psychiatric data to produce concrete results. Stephan's current GWAS research focuses on schizophreniabipolar disordermajor depressive disorder, autism spectrum disorder , attention deficit hyperactivity disorder, and cross-disease analyses. In addition to this research project, Stephan is collaborating with a plethora of additional GWAS groups (mostly consortias) for human traits, like HIVCrohn's DiseaseAMD (age-related macular degeneration),Psychopharmacogenetics, smoking, height, weight, sudden cardiac death, strokeanxiety,multiple sclerosis, and restless legs syndrome.